A lateral radiograph is shown in Figure 34. captopril, azathioprine. Either increases effects of the other by pharmacodynamic synergism. AO teaching video: Patella tendon bearing cast (PTB) 2. Dextroamphetamine may decrease the antihypertensive effects of ACE Inhibitors. Gloucester Soldiers Memorial Hospital Both drugs lower blood pressure. Combo of ACE inhibitors and injectable gold has caused rare cases of nitritoid reaction (flushing, N/V, hypot'n). Both drugs lower blood pressure. The mechanism of these interactions is likely related to the ability of NSAIDs to reduce the synthesis of vasodilating renal prostaglandins. Avoid or Use Alternate Drug. Both drugs lower blood pressure. Use Caution/Monitor. Monitor blood pressure. Either increases toxicity of the other by Other (see comment). If youre looking for a quality wraparound knee brace, you might check the offerings from Shock Doctor. Monitor BP. Wyong Public Hospital (OBQ18.58) amobarbital increases effects of captopril by pharmacodynamic synergism. Monitor Closely (1)paliperidone, captopril. WARNING: This drug can cause serious (possibly fatal) harm to an unborn baby if used during pregnancy. Minor (1)promazine increases effects of captopril by unspecified interaction mechanism. Comment: Coadministration increases risk of angioedema. Increase ACE inhibitor induced cough. The knee is made up of the lower end of the thighbone (femur), the upper end of the shinbone (tibia), and the kneecap (patella). captopril, gold sodium thiomalate. Minor (1)tamsulosin, captopril. Monitor Closely (1)iloperidone, captopril. He was treated initially with external fixation for 11 days before his soft-tissues would permit definitive open internal fixation. captopril increases effects of insulin NPH by pharmacodynamic synergism. Monitor glycemic control especially during the first month of treatment with an ACE inhibitor. Monitor Closely (1)captopril increases effects of insulin lispro by pharmacodynamic synergism. Modify Therapy/Monitor Closely. Both drugs lower blood pressure. Use Caution/Monitor. amiodarone, captopril. Monitor blood pressure. Use Caution/Monitor. captopril, celecoxib. Either increases effects of the other by pharmacodynamic synergism. Monitor Closely (1)captopril, meloxicam. (OBQ09.77) Cobicistat is a CYP2D6 inhibitor; caution with CYP2D6 substrates for which elevated plasma concentrations are associated with serious and/or life-threatening events. The surgeon should pay special attention to which of the following due to the nature of the deformity and preferred surgical technique? The mechanism of these interactions is likely related to the ability of NSAIDs to reduce the synthesis of vasodilating renal prostaglandins. Monitor blood pressure. Monitor blood pressure. Serious - Use Alternative (1)olmesartan, captopril. DRUG INTERACTIONS: See also Precautions section.Drug interactions may change how your medications work or increase your risk for serious side effects. aluminum hydroxide decreases effects of captopril by unspecified interaction mechanism. diflunisal, captopril. Tottenham Hospital Use Caution/Monitor. eprosartan, captopril. Either increases effects of the other by pharmacodynamic synergism. Comment: May result in renal function deterioration, particularly in elderly or volume depleted individuals. sodium sulfate/?magnesium sulfate/potassium chloride increases toxicity of captopril by Other (see comment). Either increases effects of the other by pharmacodynamic synergism. captopril, levodopa. Use Caution/Monitor. Comment: May result in renal function deterioration, particularly in elderly or volume depleted individuals.Serious - Use Alternative (1)piroxicam, captopril. Use Caution/Monitor. ACE inhibitors may enhance the adverse/toxic effect of iron dextran complex, specifically anaphylactic type reactions. Comment: Low molecular weight heparins may suppress adrenal aldosterone secretion, which can potentially cause hyperkalemia. Monitor blood pressure. Either increases effects of the other by pharmacodynamic synergism. Avoid or Use Alternate Drug. Finley Hospital & Community Health Centre pharmacodynamic antagonism. Additive hypotensive effects. captopril increases effects of albiglutide by unknown mechanism. icatibant decreases effects of captopril by pharmacodynamic antagonism. Monitor Closely (1)clomipramine, captopril. Tell your doctor right away if you notice any of the following serious side effects: nausea/vomiting that doesn't stop, yellowing eyes/skin, dark urine, severe stomach/abdominal pain.A very serious allergic reaction to this drug is rare. The ends of these three bones are covered with articular cartilage, a smooth substance that protects the bones and enables them to move easily within the joint. Monitor blood glucose. Arthroscopic microfracture drilling. 2 Pack Copper Fit Health Unisex Arch Relief plus with Built-In Orthotic Support. Use Caution/Monitor. NSAIDs may diminish the antihypertensive effect of ACE inhibitors. a long leg cast with the knee fully extended. ketorolac intranasal, captopril. Comment: May result in renal function deterioration, particularly in elderly or volume depleted individuals.Serious - Use Alternative (1)nabumetone, captopril. Monitor blood pressure and renal function. Use Caution/Monitor. Use Caution/Monitor. Monitor blood pressure. Minor (1)iron sucrose, captopril. Risk of hyperkalemia. captopril increases effects of tolbutamide by pharmacodynamic synergism. Comment: Low molecular weight heparins may suppress adrenal aldosterone secretion, which can potentially cause hyperkalemia. Use Caution/Monitor. The mechanism of these interactions is likely related to the ability of NSAIDs to reduce the synthesis of vasodilating renal prostaglandins. Use Caution/Monitor. Monitor Closely (1)saxagliptin increases toxicity of captopril by Mechanism: unspecified interaction mechanism. (SBQ12FA.2) A 22-year-old male presents 4 weeks following open reduction and internal fixation of his unstable ankle fracture. Either increases toxicity of the other by Mechanism: pharmacodynamic synergism. Performing an isolated release of the popliteus tendon during a total knee arthroplasty is most appropriate in which of the following scenarios? Either increases toxicity of the other by pharmacodynamic synergism. dacomitinib will increase the level or effect of captopril by affecting hepatic enzyme CYP2D6 metabolism. captopril, bretylium. captopril, triamterene. He proceeds to correct the contracture by making an additional 2mm cut off of the tibia and is successful in achieving full extension. captopril, indomethacin. The mechanism of these interactions is likely related to the ability of NSAIDs to reduce the synthesis of vasodilating renal prostaglandins. nesiritide, captopril. Both drugs lower blood pressure. Use Caution/Monitor. sodium bicarbonate decreases effects of captopril by unspecified interaction mechanism. Either increases toxicity of the other by pharmacodynamic synergism. )This medication passes into breast milk but is unlikely to harm a nursing infant. Monitor Closely (1)rolapitant will increase the level or effect of captopril by affecting hepatic enzyme CYP2D6 metabolism. Either increases effects of the other by pharmacodynamic synergism. Use Caution/Monitor. aliskiren, captopril. Either increases effects of the other by pharmacodynamic synergism. capsicum, captopril. Tenterfield Community Hospital Either increases toxicity of the other by Other (see comment). https://profreg.medscape.com/px/getpracticeprofile.do?method=getProfessionalProfile&urlCache=aHR0cHM6Ly9yZWZlcmVuY2UubWVkc2NhcGUuY29tL2RydWcvY2Fwb3Rlbi1jYXB0b3JpbC1jYXB0b3ByaWwtMzQyMzE1, View explanations for tiers and Minor/Significance Unknown. Mechanism: pharmacodynamic synergism. Radiographs are shown in Figures A and B. You should not become pregnant while using captopril. Monitor blood glucose. Either increases toxicity of the other by Other (see comment). Both drugs lower blood pressure. Use Caution/Monitor. Use Caution/Monitor. Contraindicated (1)captopril decreases effects of aliskiren by Other (see comment). Use Caution/Monitor. Either increases effects of the other by pharmacodynamic synergism. Use Caution/Monitor. Copyright 2022 Lineage Medical, Inc. All rights reserved. Comment: May result in renal function deterioration, particularly with high dose aspirin, elderly or volume depleted individuals. Performing a medial tibial reduction osteotomy. Mechanism: pharmacodynamic synergism. Free shipping. Which of the following injuries could be appropriately managed with a long arm posterior splint for 8-12 days, followed by protected range of motion exercises? Use Caution/Monitor. Serious - Use Alternative (1)irbesartan, captopril. sulfasalazine decreases effects of captopril by pharmacodynamic antagonism. (OBQ08.208) Monitor blood pressure. NSAIDs may diminish the antihypertensive effect of ACE inhibitors. 2021 California Orthopaedic Association Annual Meeting, ISTA: Emerging Technologies in Arthroplasty 2021, Conversion of Sagittal Functional Safe Zone to Coronal Plane Using a Validated Mathematic Algorithm: the Reason to Failure of Lewinnek Safe Zone - Tanghao, MD, MRCSEd, ReconTKA Coronal Plane Balancing (ft. Dr. Doug Dennis). Boorowa District Hospital Use Caution/Monitor. from ASIS curve inferiorly in the direction of the lateral patella for 8-10 cm ; Superficial dissection identify gap between sartorius and tensor fasciae latae; dissect through subcut aneous fat (avoid lateral femoral cutaneous n.) incise fascia on medial side of tensor fascia latae Avoid or Use Alternate Drug. Olecranon Fractures are rare fractures in the pediatric population and most commonly occur as a result of fall onto an outstretched hand with the elbow in flexion. A knee that is loose in extension and balanced in flexion. Methylphenidate may diminish antihypertensive effect of captopril. Nyngan Multi-Purpose Service Use Caution/Monitor. Both drugs lower blood pressure. Mechanism: pharmacodynamic synergism. Use Caution/Monitor. Use Caution/Monitor. Modify Therapy/Monitor Closely. Condobolin District Hospital Either increases effects of the other by pharmacodynamic synergism. Increased risk of orthostatic hypotension. Monitor blood pressure. Learn how to monitor your own blood pressure at home, and share the results with your doctor. Use Caution/Monitor. Either increases effects of the other by pharmacodynamic synergism. Minor (1)tizanidine increases effects of captopril by pharmacodynamic synergism. Bourke District Hospital Use Caution/Monitor. Avoid or Use Alternate Drug. Both drugs lower blood pressure. Either increases toxicity of the other by Other (see comment). clofarabine, captopril. These braces often have a patella hole over the knee cap. The mechanism of these interactions is likely related to the ability of NSAIDs to reduce the synthesis of vasodilating renal prostaglandins. Either increases toxicity of the other by pharmacodynamic synergism. Use Caution/Monitor. indapamide, captopril. Monitor blood pressure. ACE inhibitors may enhance the adverse/toxic effect of iron dextran complex, specifically anaphylactic type reactions. IMPORTANT: HOW TO USE THIS INFORMATION: This is a summary and does NOT have all possible information about this product. Use Caution/Monitor. Monitor blood pressure and adjust dose of antihypertensive agent as needed. pharmacodynamic antagonism. Use Caution/Monitor. Her upper extremity neurovascular exam shows no deficits. Monitor blood pressure. Closed versus open reduction is indicated for acute dislocations. Monitor Closely (1)captopril, furosemide. Minor/Significance Unknown. Dual blockade of renin-angiotensin system increases risks of hypotension, hyperkalemia, and renal impairment. Avoid coadministration with other drugs that decrease pulse or blood pressure to mitigate risk of excessive bradycardia and hypotension. Use Caution/Monitor.voclosporin, captopril. Monitor blood pressure. captopril, pregabalin. Monitor blood glucose. ACEP Member Login. open reduction and tension band fixation. Minor (1)thalidomide, captopril. Monitor Closely (1)abiraterone increases levels of captopril by affecting hepatic enzyme CYP2D6 metabolism. The mechanism of these interactions is likely related to the ability of NSAIDs to reduce the synthesis of vasodilating renal prostaglandins. Monitor blood glucose. Use Caution/Monitor. Monitor Closely (1)enoxaparin increases toxicity of captopril by Other (see comment). Monitor glycemic control especially during the first month of treatment with an ACE inhibitor. Avoid or Use Alternate Drug. ibuprofen IV, captopril. Monitor Closely (1)icatibant decreases effects of captopril by pharmacodynamic antagonism. Monitor blood pressure and renal function. Gilgandra Multi-Purpose Health Service Talk to your pharmacist for more details.Before using this medication, tell your doctor or pharmacist your medical history, especially of: history of an allergic reaction that included swelling of the face/lips/tongue/throat (angioedema), blood filtering procedures (such as LDL apheresis, dialysis), collagen vascular disease (such as lupus, scleroderma), high level of potassium in the blood.This drug may make you dizzy. NSAIDs may diminish the antihypertensive effect of ACE inhibitors. Avoid or Use Alternate Drug. thalidomide, captopril. Monitor blood pressure. Monitor Closely (1)eliglustat increases levels of captopril by affecting hepatic enzyme CYP2D6 metabolism. Comment: May result in renal function deterioration, particularly in elderly or volume depleted individuals. (OBQ13.135) A 34-old-male was involved in a high speed MVC. Either increases effects of the other by pharmacodynamic synergism. Monitor blood glucose. Either increases effects of the other by pharmacodynamic synergism. secobarbital, captopril. Barraba Multi Purpose Service Use Caution/Monitor. Both drugs lower blood pressure. Monitor Closely (1)phenobarbital, captopril. The mechanism of these interactions is likely related to the ability of NSAIDs to reduce the synthesis of vasodilating renal prostaglandins. In patients who are elderly, volume-depleted (including those on diuretic therapy), or with compromised renal function, coadministration of ACE-inhibitors with drugs that affect RAAS may increase the risk of renal impairment (including acute renal failure) and cause loss of antihypertensive effect. Either increases effects of the other by pharmacodynamic synergism. Monitor Closely (1)captopril increases toxicity of lithium by unknown mechanism. Use Caution/Monitor. Use Caution/Monitor. Risk of hypotension. NSAIDs may diminish the antihypertensive effect of ACE inhibitors. Arthroplasty Preoperative Medical Optimization, Idiopathic Transient Osteoporosis of the Hip (ITOH), THA Pseudotumor (Metal on Metal Reactions), TKA Postoperative Rehabilitation & Outpatient Management. Use Caution/Monitor. Monitor blood pressure. Both drugs decrease blood glucose. Monitor blood pressure and renal function. Both drugs lower blood pressure. This video has been medically reviewed by Laura Campedelli, PT, DPT. captopril, insulin degludec/insulin aspart. Use Caution/Monitor. If alternative therapy cannot be used, exercise caution and consider a dose reduction of the CYP2D6 substrate. The mechanism of these interactions is likely related to the ability of NSAIDs to reduce the synthesis of vasodilating renal prostaglandins. Monitor blood glucose. Aprotinin may diminish the blood pressure lowering effects of ACE Inhibitors. (OBQ09.57) lurasidone increases effects of captopril by Other (see comment). Monitor Closely (1)captopril, nabumetone. Campbell Hospital, Coraki pharmacodynamic antagonism. cariprazine, captopril. Werris Creek Community Hospital Comment: May result in renal function deterioration, particularly in elderly or volume depleted individuals. captopril, ketorolac intranasal. Minor/Significance Unknown. pharmacodynamic antagonism. Either increases effects of the other by pharmacodynamic synergism. azilsartan, captopril. Either increases toxicity of the other by pharmacodynamic synergism. Monitor Closely (1)sodium bicarbonate decreases effects of captopril by unspecified interaction mechanism. Exaggerated first dose hypotensive response. captopril, phenoxybenzamine. Hornsby Ku-ring-gai Hospital NSAIDs may diminish the antihypertensive effect of ACE inhibitors. Avoid or Use Alternate Drug. Placing the components in a kinematic alignment (compared to neutral mechanical alignment) would result in which of the following? Minor/Significance Unknown. Monitor blood pressure. Each drug may cause hypotension. Nonoperative treatment with a sling and unrestricted activity in 3 months, Open reduction in the operating room with thoracic surgery back-up, Closed reduction in the office with local anesthetic, Closed reduction in the operating room with thoracic surgery back-up, Nonoperative treatment with immediate unrestricted active range of motion of the shoulder. captopril increases toxicity of ciprofloxacin by Mechanism: unspecified interaction mechanism. Keep all medications away from children and pets.Do not flush medications down the toilet or pour them into a drain unless instructed to do so. May increase risk for allergic or hypersensitivity reactions to allopurinol Monitor for symptoms of hypersensitivty reactions if both drugs must be used together. pharmacodynamic antagonism. Coadministration with drugs that reduce renal function or compete for active tubular secretion may increase serum concentrations of either entecavir or the coadministered drug. commonly, these are generic drugs. This drug is available at the lowest co-pay. Treatment depends on the degree of angulation and is surgical if angulation remains greater than 30 degrees after closed reduction is attempted. Coadministration may result in a significant decrease in renal function. Increased risk of nephrotoxicity. Use Caution/Monitor. Monitor blood pressure. Use Caution/Monitor. Dual blockade of renin-angiotensin system increases risks of hypotension, hyperkalemia, and renal impairment. Use Caution/Monitor. Mechanism: unspecified interaction mechanism. Sodium citrate/citric acid may decrease absorption of captopril. Either increases toxicity of the other by Other (see comment). Use Caution/Monitor. NSAIDs may diminish the antihypertensive effect of ACE inhibitors. Breaking your femur takes a lot of force, so itll probably be obvious if you break it. Both drugs lower blood pressure. tolfenamic acid decreases effects of captopril by pharmacodynamic antagonism. Monitor blood pressure. NSAIDs may diminish the antihypertensive effect of ACE inhibitors. Monitor Closely (1)iloprost, captopril. Both drugs decrease blood glucose. The menisci are located between the femur and tibia. All of the following are intraoperative techniques to treat a flexion contracture in total knee arthroplasty EXCEPT: (OBQ09.153) Administer ACE inhibitor at least 2 hr before or after lanthanum. Monitor blood pressure. Comment: May result in renal function deterioration, particularly in elderly or volume depleted individuals. A patient comes to the office with a flexion contracture following a total knee arthroplasty that has resulted in an unsatisfactory outcome. Monitor Closely (1)morphine, captopril. Inverell District Hospital Both drugs lower blood glucose. Either increases toxicity of the other by pharmacodynamic synergism. Bowral Hospital Aprotinin may diminish the blood pressure lowering effects of ACE Inhibitors. Either increases effects of the other by pharmacodynamic synergism. Both drugs lower blood pressure. Monitor potassium. The surgeon has all the trial components in place and recognizes that the soft tissues are balanced in the coronal plane, but the knee is Monitor Closely (1)captopril, torsemide. Initial: 25 mg PO q8-12hr, increase gradually based on response (may start lower in some patients), Initial: 6.25-12.5 mg PO q8hr in conjunction with cardiac glycoside and diuretic therapy, 6.25 mg PO initially followed by 12.5 mg q8hr, Increase to 25 mg PO q8hr over next few days; THEN, Beneficial for many patients at risk for heart disease; reduces risk of MI, stroke, diabetic nephropathy , microalbuminuria, new onset DM, Consider starting an ACE inhibitor in high-risk patients, even if no HTN or CHF, May prolong survival in CHF, may preserve renal function in DM, Requires weeks for full effect; to start, use low dose and titrate every 1-2wk, Neonates: 0.05-0.1 mg/kg/dose q8-24hr, titrate dose up to 0.5 mg/kg/dose q6-24hr, Infants: 0.15-0.3 mg/kg/dose; titrate dose upward to maximum 6 mg/kg/day in 1-4 divided doses; 2.5-6 mg/kg/day usually required, Children: 0.3-0.5 mg/kg/dose; titrate to maximum 6 mg/kg/day divided q6-12hr, Older children: 6.25-12.5 mg/dose q12-24hr; titrate to no more than 6 mg/kg/day divided q6-12hr, Adolescents: 12.5-25 mg/dose q8-12hr; may increase by 25 mg/dose q1-2Weeks to maximum 450 mg/day. Radial head and neck fractures in children are a relatively common traumatic injury that usually affects the radial neck (metaphysis) in children 9-10 years of age. Mechanism: pharmacodynamic synergism. A 3-D computed tomography image is shown in Figure A. The mechanism of these interactions is likely related to the ability of NSAIDs to reduce the synthesis of vasodilating renal prostaglandins. The surgeon is seated on a low chair. Canterbury Hospital remifentanil, captopril. captopril and canagliflozin both increase serum potassium. It can help decrease nociceptive input to the If a P-gp inhibitor must be used, reduce the venetoclax dose by at least 50%. Minor/Significance Unknown. Increased risk of advers/toxic effects, specifically increased risk of angioedema. Comment: ACE inhibitors may increase hypoglycemic effect. Monitor Closely (1)amobarbital increases effects of captopril by pharmacodynamic synergism. Monitor glycemic control especially during the first month of treatment with an ACE inhibitor. Monitor blood pressure. Minor (1)brimonidine increases effects of captopril by pharmacodynamic synergism. When amifostine is used at chemotherapeutic doses, withhold blood pressure lowering medications for 24 hr prior to amifostine; if blood pressure lowering medication cannot be withheld, do not administer amifostine. Most people with high blood pressure do not feel sick.For the treatment of high blood pressure, it may take up to 2 weeks before you get the full benefit of this medication. Monitor Closely (1)sitagliptin, captopril. (OBQ13.135) A 34-old-male was involved in a high speed MVC. Risk of hyperkalemia. Dual blockade of renin-angiotensin system increases risks of hypotension, hyperkalemia, and renal impairment. indomethacin, captopril. Use Caution/Monitor. Methamphetamine may decrease the antihypertensive effects of ACE Inhibitors. Monitor Closely (1)ropivacaine increases effects of captopril by Mechanism: pharmacodynamic synergism. Either increases toxicity of the other by pharmacodynamic synergism. A 33-year-old female is diagnosed with spontaneous atraumatic subluxation of the sternoclavicular joint. givosiran will increase the level or effect of captopril by affecting hepatic enzyme CYP2D6 metabolism. arsenic trioxide, captopril. Either increases effects of the other by pharmacodynamic synergism. Either increases toxicity of the other by pharmacodynamic synergism. Bombala Multi Purpose Service captopril, meloxicam. 5% Boggabri Multi-Purpose Service If you are planning pregnancy, become pregnant, or think you may be pregnant, contact your doctor right away. Either increases toxicity of the other by pharmacodynamic synergism. Examination reveals that the knee is stable in full extension but has gross anteroposterior instability at 90 degrees of flexion. Either increases effects of the other by pharmacodynamic synergism. Current Concepts of Revision Hip and Revision Knee Reconstruction Surgery Invited Lecture on Revision Hip and Knee Surgery, Academic, 3rd King Hussein Cancer Center Conference on Limb Salvage Surgery, Amman, Jordan (10/01/2018) King Hussein Cancer Center Periprosthetic Hip and Knee Infections - Diagnosis and Management sitagliptin, captopril. Contraindicated. Both drugs decrease blood glucose. Monitor Closely (1)captopril, magnesium salicylate. Use Caution/Monitor. Exam reveals ecchymosis and swelling over the patella and an extensor lag. Angiotensin converting enzyme (ACE) inhibitors dilate arteries and veins by competitively inhibiting the conversion of angiotensin I to angiotensin II (a potent endogenous vasoconstrictor) and by inhibiting bradykinin metabolism; these actions result in preload and afterload reductions on the heart, ACE inhibitors also promote sodium and water excretion by inhibiting angiotensin-II induced aldosterone secretion; elevation in potassium may also be observed, ACE inhibitors also elicit renoprotective effects through vasodilation of renal arterioles, ACE inhibitors reduce cardiac and vascular remodeling associated with chronic hypertension, heart failure, and myocardial infarction, Half-life: 1.9 hr (healthy); 2.06 (heart failure); 20-40 hr (anuria); significantly increase in CrCl <20 mL/min, Onset: PO: initial response: 15-30 min; peak response: 60-90 min, Metabolites: captopril-cysteine disulfide (inactive). Most Either increases effects of the other by pharmacodynamic synergism. The mechanism of these interactions is likely related to the ability of NSAIDs to reduce the synthesis of vasodilating renal prostaglandins. isoflurane, captopril. Minor/Significance Unknown. Monitor Closely (1)captopril, bretylium. Both drugs lower blood pressure. She refuses to move her arm due to the pain but is neurovascularly intact distally. captopril, insulin inhaled. patella increases power and mechanical advantage of extensor mechanism by 30-50% by displacing it anteriorly away from the center of rotation. (SBQ06TR.62) A 35-year-old zookeeper fell 10 feet while preparing an exhibit for a grand reopening, landing on his left arm. Either increases toxicity of the other by pharmacodynamic synergism. Either increases toxicity of the other by pharmacodynamic synergism. SIDE EFFECTS: Dizziness, lightheadedness, or loss of taste may occur as your body adjusts to the medication. Monitor Closely (2)captopril, alfuzosin. (OBQ05.223) Mechanism: pharmacodynamic synergism. Adjust dose of drugs that are CYP2D6 substrates as necessary. Hillston District Hospital captopril, bumetanide. Coolah Multi-Purpose Health Service Coolamon-Ganmain Health Service tamsulosin, captopril. The following chart shows different conditions found with the trials in place and the treatment strategy for each condition. Coadministration may result in a significant decrease in renal function. Which of the following injuries could be appropriately managed with a long arm posterior splint for 8-12 days, followed by protected range of motion exercises? captopril, insulin degludec. Terms of Use | Either increases effects of the other by pharmacodynamic synergism. Share cases and questions with Physicians on Medscape consult. Either increases effects of the other by pharmacodynamic synergism. Either increases effects of the other by pharmacodynamic synergism. Sutherland Hospital & Community Health Service Balranald District Hospital Use Caution/Monitor. Positioning. Monitor Closely (1)captopril increases effects of insulin NPH by pharmacodynamic synergism. Monitor blood pressure. captopril, silodosin. (SBQ10PE.88.1) piroxicam, captopril. Monitor blood glucose. pharmacodynamic antagonism. She denies any complaints of respiratory distress or upper extremity paresthesias. 1,2 The primary endpoint was incidence of new Monitor Closely (1)bupivacaine, captopril. Surgical Techniques and Instrumentation in Total Knee Arthroplasty. Either increases effects of the other by Mechanism: pharmacodynamic synergism. A lateral radiograph is shown in Figure 7. Modify Therapy/Monitor Closely. Use Caution/Monitor. Use Caution/Monitor. The Cootamundra Hospital The flexion gap is well balanced. (SBQ10PE.88.1) A 5-year-old girl presents to the emergency room after a fall off a playground with right elbow pain. aspirin/citric acid/sodium bicarbonate decreases effects of captopril by pharmacodynamic antagonism. Monitor blood pressure. Knee Brace Support Patella Gel Strap Sport Joint Pain Relief Arthritis Running. Wagga Wagga Base Hospital fedratinib will increase the level or effect of captopril by affecting hepatic enzyme CYP2D6 metabolism. ACE inhibitors may increase hypoglycemic effect. Comment: May result in renal function deterioration, particularly in elderly or volume depleted individuals. The mechanism of these interactions is likely related to the ability of NSAIDs to reduce the synthesis of vasodilating renal prostaglandins. Coadministration may result in a significant decrease in renal function. captopril and finerenone both increase serum potassium. Monitor Closely (1)captopril, ibuprofen. CT studies are generally required to assess for direction of displacement. Comment: May result in renal function deterioration, particularly in elderly or volume depleted individuals. Avoid or Use Alternate Drug. Yass District Hospital Monitor Closely (1)dexmethylphenidate decreases effects of captopril by pharmacodynamic antagonism. Coadministration with blood pressure lowering agents may increase the risk and severity of hypotension associated with amifostine. Monitor Closely (2)voclosporin and captopril both increase serum potassium. NSAIDs may diminish the antihypertensive effect of ACE inhibitors. Dual blockade of renin-angiotensin system increases risks of hypotension, hyperkalemia, and renal impairment. Management should consist of. Dual blockade of renin-angiotensin system increases risks of hypotension, hyperkalemia, and renal impairment. Either increases effects of the other by pharmacodynamic synergism. Either increases effects of the other by pharmacodynamic synergism. Avoid or Use Alternate Drug. Either increases effects of the other by pharmacodynamic synergism. iloperidone, captopril. Coadministration may result in a significant decrease in renal function. Use Caution/Monitor. Either increases effects of the other by Mechanism: pharmacodynamic synergism. Use Caution/Monitor. Both drugs decrease blood pressure. Either increases effects of the other by pharmacodynamic synergism. NSAIDs may diminish the antihypertensive effect of ACE inhibitors. Monitor blood pressure. Her symptoms have been present for nearly a decade, and she has failed an appropriate course of conservative management but remains persistently symptomatic. Minor/Significance Unknown. Coadministration may result in a significant decrease in renal function. This document does not contain all possible drug interactions. Use Caution/Monitor. tolmetin, captopril. This can lead to normalized muscular tone and can also help improve athletic performance. Monitor Closely (1)captopril, insulin degludec/insulin aspart. Monitor Closely (1)sevoflurane increases effects of captopril by pharmacodynamic synergism. Monitor blood pressure and renal function. Monitor Closely (1)captopril, gold sodium thiomalate. Copyright 2022 Lineage Medical, Inc. All rights reserved. Avoid or Use Alternate Drug. Modify Therapy/Monitor Closely. The mechanism of these interactions is likely related to the ability of NSAIDs to reduce the synthesis of vasodilating renal prostaglandins. captopril increases effects of insulin detemir by pharmacodynamic synergism. Both drugs lower blood pressure. sildenafil, captopril. I've noticed a tremendous reduction in pain and swelling of my Achilles tendons. Use Caution/Monitor. but if degree of reduction loss is small, may not affect union. dextroamphetamine decreases effects of captopril by pharmacodynamic antagonism. Either increases toxicity of the other by Other (see comment). Monitor Closely (1)captopril and canagliflozin both increase serum potassium. Avoid or Use Alternate Drug. Either increases effects of the other by Mechanism: pharmacodynamic synergism. Compare formulary status to other drugs in the same class. bromocriptine, captopril. Monitor Closely (1)avanafil increases effects of captopril by pharmacodynamic synergism. Either increases toxicity of the other by Other (see comment). Consult your pharmacist or local waste disposal company. Monitor Closely (1)captopril, ethacrynic acid. Either increases effects of the other by pharmacodynamic synergism. Wollongong Hospital Minor (1)clofarabine, captopril. Use Caution/Monitor. Mechanism: pharmacodynamic synergism. Comment: May result in renal function deterioration, particularly in elderly or volume depleted individuals. Use Caution/Monitor. rasagiline, captopril. (OBQ13.53) olmesartan, captopril. Dual blockade of renin-angiotensin system increases risks of hypotension, hyperkalemia, and renal impairment. Monitor Closely (1)captopril increases effects of tolazamide by pharmacodynamic synergism. Use Caution/Monitor. Patellar sleeve fractures are a rare injury seen in children between 8 and 12 years of age characterized by a traumatic separation between the cartilage "sleeve" and the main part of the ossified patella. Use Caution/Monitor. Call +44 (0)330 3530238 7% (262/3500) 3. The Children's Hospital at Westmead captopril, meclofenamate. Use Caution/Monitor. Monitor blood pressure. It can help decrease nociceptive input to the Monitor blood glucose. Monitor Closely (1)aldesleukin, captopril. Avoid or Use Alternate Drug. Use Caution/Monitor. Monitor Closely (1)captopril, insulin degludec. captopril, doxazosin. Monitor Closely (1)phentermine decreases effects of captopril by pharmacodynamic antagonism. WOPOKY Patella Tendon Knee Strap, Knee Pain Relief for Torn Meniscus ACL MCL Arthritis Tendonitis, Knee Brace Support for Working Out Weightlifting Squats Running Jumpers Tennis. Perform open reduction and internal fixation of the radius, then assess the distal radioulnar joint for instability, and percutaneously fix the distal radioulnar joint if instability persists. Murrumburrah-Harden District Hospital Both drugs lower blood pressure. Use Caution/Monitor. Use Caution/Monitor. . Talk to your doctor if you are using marijuana (cannabis).To reduce the risk of dizziness and lightheadedness, get up slowly when rising from a sitting or lying position.Too much sweating, diarrhea, or vomiting may cause dehydration and increase your risk of lightheadedness. ACE inhibitor induced Na+ depletion may increase reabsorption of lithium from renal tubule. Monitor blood glucose. captopril increases effects of insulin aspart by pharmacodynamic synergism. NSAIDs may diminish the antihypertensive effect of ACE inhibitors. choline magnesium trisalicylate, captopril. Minor (1)desflurane, captopril. thioridazine increases effects of captopril by unspecified interaction mechanism. Either increases toxicity of the other by pharmacodynamic synergism. pharmacodynamic antagonism. Both drugs lower blood pressure. Both drugs decrease blood pressure. Either increases toxicity of the other by Other (see comment). They are usually stable following closed reduction, They require fusion to hold the reduction, They are rarely symptomatic when left unreduced, They should be treated acutely with medial clavicle excision. sacubitril/valsartan, captopril. aspirin, captopril. The Journal of the American Academy of Dermatology (JAAD), the official scientific publication of the American Academy of Dermatology (AAD), aims to satisfy the educational needs of the dermatology community.As the specialty's leading journal, JAAD features original, peer-reviewed articles emphasizing: A 33-year-old secretary presents three months after a motor vehicle collision with a mild asymmetry to her sternal area and difficulty swallowing. Minor/Significance Unknown. Either increases effects of the other by pharmacodynamic synergism. Do not start, stop, or change the dosage of any medicines without your doctor's approval.Some products that may interact with this drug include: aliskiren, certain drugs that weaken the immune system/increase the risk of infection (such as everolimus, sirolimus), lithium, drugs that may increase the level of potassium in the blood (such as ARBs including losartan/valsartan, birth control pills containing drospirenone), sacubitril.Some products have ingredients that could raise your blood pressure or worsen your heart failure. Monitor Closely (1)elvitegravir/cobicistat/emtricitabine/tenofovir DF increases levels of captopril by affecting hepatic enzyme CYP2D6 metabolism. Both drugs decrease blood glucose and blood pressure. Monitor blood pressure. pharmacodynamic antagonism. Increased risk of nephrotoxicity. Use Caution/Monitor. Use Caution/Monitor. Her symptoms have been present for nearly a decade, and she has failed an appropriate course of conservative management but remains persistently symptomatic. Minor/Significance Unknown. Use Caution/Monitor. Monitor Closely (1)tranylcypromine increases effects of captopril by pharmacodynamic synergism. Comment: May result in renal function deterioration, particularly in elderly or volume depleted individuals.Serious - Use Alternative (1)indomethacin, captopril. pharmacodynamic antagonism. Either increases toxicity of the other by Other (see comment). Bulli Hospital Both drugs lower blood pressure. Arthroscopic open reduction and internal fixation. Monitor blood pressure. Trauma; Spine; Shoulder & Elbow; Knee & Sports; Pediatrics; Recon; Hand; Foot & Ankle; lesions in lateral femoral condyle and patella have poorer prognosis. An 19-year-old male presents to the emergency room following an motor vehicle accident as an unrestrained driver. Either increases toxicity of the other by Mechanism: pharmacodynamic synergism. Minor/Significance Unknown. Prince of Wales Hospital Monitor blood pressure and renal function. Monitor blood pressure. Diagnosis is made with radiographs of the knee. Increased risk of nephrotoxicity. Minor/Significance Unknown. Use Caution/Monitor. captopril increases effects of chlorpropamide by pharmacodynamic synergism. conivaptan, captopril. Either increases effects of the other by pharmacodynamic synergism. Use Caution/Monitor. tizanidine increases effects of captopril by pharmacodynamic synergism. Minor (1)agrimony increases effects of captopril by pharmacodynamic synergism. Either increases effects of the other by pharmacodynamic synergism. Either increases effects of the other by pharmacodynamic synergism. Both drugs lower blood pressure. captopril increases toxicity of allopurinol by Mechanism: unspecified interaction mechanism. Both drugs lower blood pressure. Monitor Closely (1)sildenafil, captopril. Monitor Closely (1)captopril, ketorolac. Either increases toxicity of the other by pharmacodynamic synergism. Wilcannia Multi-Purpose Service A distal femoral augment is used to restore the joint line. Use Caution/Monitor. Monitor blood ressure. Monitor Closely (1)serdexmethylphenidate/dexmethylphenidate decreases effects of captopril by pharmacodynamic antagonism. Bellingen River District Hospital Monitor potassium. Avoid or Use Alternate Drug. Westmead Hospital Monitor blood pressure. Use Caution/Monitor. Comment: Low molecular weight heparins may suppress adrenal aldosterone secretion, which can potentially cause hyperkalemia. The mechanism of these interactions is likely related to the ability of NSAIDs to reduce the synthesis of vasodilating renal prostaglandins. Both drugs decrease blood glucose and blood pressure. Either increases effects of the other by pharmacodynamic synergism. captopril, fenoprofen. The mechanism of these interactions is likely related to the ability of NSAIDs to reduce the synthesis of vasodilating renal prostaglandins. The Maitland Hospital Avoid or Use Alternate Drug. Use Caution/Monitor. Avoid or Use Alternate Drug. captopril increases levels of digoxin by unspecified interaction mechanism. Browse our listings to find jobs in Germany for expats, including jobs for English speakers or those in your native language. Minor (1)promethazine increases effects of captopril by unspecified interaction mechanism. Avoid or Use Alternate Drug. Monitor blood pressure. Both drugs lower blood pressure. View the formulary and any restrictions for each plan. Comment: May result in renal function deterioration, particularly in elderly or volume depleted individuals.Serious - Use Alternative (1)mefenamic acid, captopril. Use Caution/Monitor. Avoid or Use Alternate Drug. Post Video; Podcasts. Blood pressure lowering drugs may enhance the hypotensive effect of duloxetine. Perform open reduction and internal fixation of the radius, then assess the distal radioulnar joint for instability, and percutaneously fix the distal radioulnar joint if instability persists. Monitor Closely (1)butalbital, captopril. Monitor blood pressure. NSAIDs may diminish the antihypertensive effect of ACE inhibitors. Avoid or Use Alternate Drug. Coadministration may result in a significant decrease in renal function. Modify Therapy/Monitor Closely. (SAE07HK.81) potassium iodide and captopril both increase serum potassium. Stay up to date on ATP news, stories, results, videos & analysis from the team at FOX Sports -- covering your favorite players & events Both drugs decrease blood glucose. Either increases toxicity of the other by Other (see comment). Avoid or Use Alternate Drug. Minor/Significance Unknown. Either increases effects of the other by pharmacodynamic synergism. Monitor blood glucose. Monitor Closely (1)indapamide, captopril. Use Caution/Monitor. He has pain and swelling at the elbow without evidence of instability. Monitor blood pressure. Modify Therapy/Monitor Closely. phenobarbital, captopril. The patient is then evaluated by a keen orthopedic resident in the emergency room who describes the zookeeper's injuries to his chief. Treatment depends on the degree of angulation and is surgical if angulation remains greater than 30 degrees after closed reduction is attempted. Monitor Closely (1)phenelzine, captopril. abiraterone increases levels of captopril by affecting hepatic enzyme CYP2D6 metabolism. TIPSUse quotes for an exact phrase match, eg:"search term" pharmacodynamic antagonism. NSAIDs decrease prostaglandin synthesis. Arthroscopic microfracture drilling. chlorpromazine increases effects of captopril by unspecified interaction mechanism. captopril, etodolac. commonly, these are "preferred" (on formulary) brand drugs. Do not double the dose to catch up. Use Caution/Monitor. Access your plan list on any device mobile or desktop. Both drugs lower blood pressure. These braces often have a patella hole over the knee cap. Contact the applicable plan In patients who are elderly, volume-depleted (including those on diuretic therapy), or with compromised renal function, coadministration of ACE-inhibitors with drugs that affect RAAS may increase the risk of renal impairment (including acute renal failure) and cause loss of antihypertensive effect. This information is not individual medical advice and does not substitute for the advice of your health care professional. Use Caution/Monitor. Monitor Closely (1)nitric oxide gas, captopril. Stay up to date on ATP news, stories, results, videos & analysis from the team at FOX Sports -- covering your favorite players & events Blacktown Hospital Either increases toxicity of the other by Other (see comment). aspirin/citric acid/sodium bicarbonate decreases effects of captopril by pharmacodynamic antagonism. Either increases toxicity of the other by Other (see comment). Exaggerated first dose hypotensive response. (OBQ06.165) Avoid or Use Alternate Drug. The mechanism of these interactions is likely related to the ability of NSAIDs to reduce the synthesis of vasodilating renal prostaglandins. Use Caution/Monitor. Use Caution/Monitor. Monitor Closely (1)captopril, phentolamine. Use Caution/Monitor. Either increases toxicity of the other by Other (see comment). Monitor blood pressure. Information last revised November 2022. Use Caution/Monitor. Kurri Kurri Hospital Rolapitant may increase plasma concentrations of CYP2D6 substrates for at least 28 days following rolapitant administration. NSAIDs decrease prostaglandin synthesis. Pambula District Hospital Either increases effects of the other by pharmacodynamic synergism. Use Caution/Monitor. Risk of hyperkalemia. Mechanism: pharmacodynamic synergism. Avoid or Use Alternate Drug. Monitor blood pressure. avanafil increases effects of captopril by pharmacodynamic synergism. Avoid coadministration with other drugs that decrease pulse or blood pressure to mitigate risk of excessive bradycardia and hypotension. Coadministration may result in a significant decrease in renal function. Either increases effects of the other by pharmacodynamic synergism. The recipient will receive more details and instructions to access this offer. Monitor Closely (1)captopril, sirolimus. Use Caution/Monitor. Minor/Significance Unknown. The menisci are located between the femur and tibia. Enhanced hypotensive effects. Use Caution/Monitor. Be sure to drink enough fluids to prevent dehydration unless your doctor directs you otherwise.Before having surgery, tell your doctor or dentist about all the products you use (including prescription drugs, nonprescription drugs, and herbal products).This product may increase your potassium levels. Injury was founded in 1969 and is an international journal dealing with all aspects of trauma care and accident surgery.Our primary aim is to facilitate the exchange of ideas, techniques and information among all members of the trauma team. Exposure of the patella and posterolateral corner. Either increases effects of the other by pharmacodynamic synergism. Comment: Coadministration increases risk of angioedema. Cobar District Hospital Use Caution/Monitor. Either increases effects of the other by decreasing renal clearance. NSAIDs may diminish the antihypertensive effect of ACE inhibitors. Inhibition and pain management: Kinesiology tape can be used to help decrease pain and muscle spasms that may occur after injury. Use Caution/Monitor. Use Caution/Monitor. Post Video; Podcasts. Both drugs lower blood pressure. Calvary Mater Newcastle Jones V. Conservative management of the post-traumatic stiff elbow: a physiotherapist's perspective. Both drugs lower blood pressure. Monitor Closely (1)potassium iodide and captopril both increase serum potassium. Minor/Significance Unknown. Either increases effects of the other by pharmacodynamic synergism. Both drugs decrease blood glucose and blood pressure. Monitor blood pressure. Avoid or Use Alternate Drug. Either increases toxicity of the other by Other (see comment). Monitor blood pressure. Either increases effects of the other by pharmacodynamic synergism. Serious - Use Alternative (1)captopril, sodium phosphates, IV. sodium sulfate/potassium sulfate/magnesium sulfate increases toxicity of captopril by Other (see comment). Either increases effects of the other by pharmacodynamic synergism. A bipartite patella is a congenital condition caused by failure of the patella to fuse. NSAIDs decrease prostaglandin synthesis. Before using potassium supplements or salt substitutes that contain potassium, consult your doctor or pharmacist.Older adults may be more sensitive to the side effects of this drug, including dizziness and increases in potassium level.Tell your doctor if you are pregnant or plan to become pregnant. Monitor blood pressure. NSAIDs may diminish the antihypertensive effect of ACE inhibitors. Use Caution/Monitor. Serious - Use Alternative (1)captopril will increase the level or effect of venetoclax by P-glycoprotein (MDR1) efflux transporter. Monitor Closely (1)captopril, chlorothiazide. Avoid or Use Alternate Drug. pharmacodynamic antagonism. Dual blockade of renin-angiotensin system increases risks of hypotension, hyperkalemia, and renal impairment. May increase risk of hypotension. Monitor glycemic control especially during the first month of treatment with an ACE inhibitor. Copyright 2022 Lineage Medical, Inc. All rights reserved. Comment: May result in renal function deterioration, particularly in elderly or volume depleted individuals. Both drugs lower blood pressure. Monitor Closely (1)tadalafil increases effects of captopril by pharmacodynamic synergism. AP and lateral radiographs are shown in Figures 12a and 12b, respectively. Urbenville Health Service Use Caution/Monitor. propofol, captopril. physical therapy for quadriceps strengthening exercises. Either increases toxicity of the other by pharmacodynamic synergism. Trimethoprim decreases urinary potassium excretion. May increase risk of hypotension. Serious - Use Alternative (1)losartan, captopril. 1,2 The primary endpoint was incidence of new Search Podcasts. amphotericin B deoxycholate, captopril. Both drugs lower blood pressure. amyl nitrite, captopril. A 63-year-old woman reports giving way of the knee and pain after undergoing primary total knee arthroplasty (TKA) 1 year ago. Use Caution/Monitor. Use Caution/Monitor. Use Caution/Monitor. Dual blockade of renin-angiotensin system increases risks of hypotension, hyperkalemia, and renal impairment. Increased risk of hyperkalemia. Either increases effects of the other by pharmacodynamic synergism. Risk of hyperkalemia. Privacy Policy | She is noted to have 6 points out of a possible 9 points on the Beighton-Horan scale. Exaggerated first dose hypotensive response. Monitor Closely (1)bendroflumethiazide, captopril. NSAIDs decrease prostaglandin synthesis. Exaggerated first dose hypotensive response. Monitor lithium levels. Either increases toxicity of the other by Other (see comment). Monitor blood pressure. Potassium salts may increase the hyperkalemic effects of ACE inhibitors; the effect may be the result of aldosterone suppression in patients receiving ACE inhibitors. Avoid or Use Alternate Drug. Monitor Closely (1)secobarbital, captopril. If you log out, you will be required to enter your username and password the next time you visit. captopril, sodium phosphates, IV. Monitor blood pressure. Use Caution/Monitor. Both drugs decrease blood glucose. NSAIDs may diminish the antihypertensive effect of ACE inhibitors. Coadministration may result in a significant decrease in renal function. captopril, salsalate. pharmacodynamic antagonism. pharmacodynamic antagonism. Use Caution/Monitor. captopril increases effects of exenatide injectable suspension by Other (see comment). Either increases effects of the other by pharmacodynamic synergism. Monitor blood pressure and renal function. Minor (1)imipramine, captopril. Monitor blood pressure. Use Caution/Monitor. Both drugs lower blood pressure. prescription products. Monitor Closely (1)captopril, terazosin. Use Caution/Monitor. diclofenac, captopril. Upsize the femoral component and add posterior augments, Move the femoral component more anteriorly. Either increases effects of the other by pharmacodynamic synergism. Avoid or Use Alternate Drug. NSAIDs may diminish the antihypertensive effect of ACE inhibitors. Use Caution/Monitor. Monitor blood pressure. They provide stability above and below the knee but very little support on the sides. He sustained an injury to his right leg as seen in Figures A and B. clozapine increases toxicity of captopril by pharmacodynamic synergism. Increased risk of advers/toxic effects, specifically increased risk of angioedema. Both drugs lower blood pressure. Serious - Use Alternative (1)valsartan, captopril. Monitor blood glucose. Molong Health Service NSAIDs may diminish the antihypertensive effect of ACE inhibitors. Use Caution/Monitor. Publishes content for an international readership on topics related to physical therapy. Lithgow Integrated Health Service The mechanism of these interactions is likely related to the ability of NSAIDs to reduce the synthesis of vasodilating renal prostaglandins. Avoid or Use Alternate Drug. captopril, terazosin. NSAIDs may diminish the antihypertensive effect of ACE inhibitors. Monitor blood pressure. Either increases effects of the other by pharmacodynamic synergism. Either increases effects of the other by pharmacodynamic synergism. Use Caution/Monitor. Monitor Closely (1)dextroamphetamine decreases effects of captopril by pharmacodynamic antagonism. 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